Much of the academic infrastructure available on the North Campus had been constructed in the 1940s and 1950s. The number of postgraduate departments, faculty, courses and number of students have since increased manifold. However, the infrastructure has not undergone any expansion worth the name in the last three or four decades. The need for extra space has been experienced acutely in the Faculty of Arts complex, where the departments of the Faculties of Arts, Social Sciences and Mathematical Sciences were located. With the passage of time this was aggravated by the expansion and diversification of faculty. Several members of faculty did not have any office space, and many others were forced to share office space. Addressing this need, two new buildings with state-of-the-art facilities have been constructed next to the Faculty of Arts. The first houses the Faculty of Mathematical Sciences. Opposite this, is the other new building which is the new home for the Faculty of Social Sciences. As a result of this, much more space has been released within the Old Faculty of Arts Complex for the members of the Faculty of Arts.

The Life Science Departments of the South Campus have been pioneers in the frontier of research, and have a longstanding need for more space for their academic and research programmes. In response to this, a new Academic Block with modern features is being constructed in the South Campus, and is nearing completion. This building will house the Life Sciences Departments. There have been several interdisciplinary and applied research, training and extension activities in the University, and some of them are being pursued through specialized Centres set up for this purpose. An Academic Research Centres Complex has come up opposite Khalsa College to house these activities. This Complex has several common facilities like an auditorium which can seat 250 persons, a number of large multi-purpose rooms which can be used for lectures, seminars, training laboratories, workshops and a cafetaria. In this building, space has been allocated for the Developing Countries Research Centre, the Women's Studies Development Centre, the Centre for Science Education and Communication, the Intellectual Property Rights Centre, the Institute of Humanities, the Centre for Psycholanalytic Studies, the Centre for Interdisciplinary Studies of Mountain and Hill Development and the Professor DS Kothari Centre for Science, Ethics and Education. One floor of this building is allocated to the Department of Education to locate its diverse activities and house its various facilities, including those under the IASE-MACESE Scheme of the Ministry of Human Resource Development, Government of India.

This is in response to the longstanding need for more space recognized right since 1979 when the Central Institute of Education merged with the University of Delhi as a full-fledged Department of Education. A Biotech Centre is being established in the South Campus with funding from the Government of Delhi. This Centre is meant to be the nucleus of University-Industry interactive research in the areas of enzymes of industrial utility, transgenic crops, diagnostics for diseases and genetic disorders. In addition, a comprehensive attempt was made to equip all faculty offices with computers connected to the campus-wide network and all classrooms with appropriate audiovisual equipment. Most newly appointed members of faculty, especially in the sciences, were provided with a seed-grant for setting up their laboratories.