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University of Delhi
 
Faculty Member Profile
 
 

ACADEMICS

Prof. Sunil Sharma

Prof.
  Professor
     North Campus, University of Delhi,
Delhi - 110007
 
     
+91-11-27666646 Ext. 191
     sk.sharma90@gmail.com
     http://www.du.ac.in/index.php?id=270&fmember=2645&

Educational Qualifications

Ph. D.

University of Delhi

1992

Thesis topic:  New Natural Products and their spectral studies

M. Sc.

University of Delhi

1986

 

B. Sc.

University of Delhi

1984

 

Career Profile

University of Massachusetts Lowell, USA

Research Scientist

2002 - 2004

Carried research in the areas of Polymer Chemistry and Nanotechnology

University of Delhi

Associate Professor

2004-2010

Teaching and research

University of Delhi

Professor

2010-present

Teaching and research

Areas of Specialization / Interest

Organic synthesis, Bio-catalysis, Chemistry of natural products, Nucleic acid chemistry, Polymer synthesis, and Nanotechnology.

Subjects Taught

2004-present: Spectroscopic techniques for identification of organic compounds, Chemistry of natural products, Chemistry of life processes, Photochemistry

Research Guidance

Supervision of awarded or submitted Doctoral Thesis - 3

Supervision of Doctoral Thesis, under progress - 4

Supervision of awarded M.Phil dissertations - 2

Publications Profile

Research papers published in Refereed/Peer Reviewed Journals

Calderon, M. et al. 2010. Biomedical applications of dendritic polyglycerols. Advanced Materials. 22: 190-218.
Priya, N. et al. 2010. Characterization of 4-methyl-2-oxo-1,2-dihydroquinolin-6-yl acetate as an effective antiplatelet agent. Bioorg. Med. Chem. 18: 4085-94.
Gupta, A. et al. 2010. Specificities of Calreticulin Transacetylase to acetoxy derivatives of benzofurans: Effect on the activation of platelet Nitric Oxide Synthase. Biochimie . doi:10.101:.
Husain, M, et al. 2010. Enantioselective biocatalytic reactions on ()-aryl alkyl ketones by native and modified PPL. Biocatalysis and Biotransformation. 28: 172-84.
Kathuria, A et al. 2010. Biocatalytic Approach for the Synthesis of Glycerol-based Nanomicellar Self-assembly Systems. Macromolecular Chemistry & Physics. 211: 239-244.
SK Sharma et al. 2009. Specificities of acetoxy derivatives of 3-alkyl-4-methylcoumarins for acetoxy drug: Protein transacetylase and their role in activation of Nitric Oxide Synthase. Bioorganic and Medicinal Chemistry. 17: 1550-1556.
Pandey, MK et al. 2008. Selective recognition of Ca2+ ions using novel polymeric phenols. Microchemical Journal. 90: 89-92.
Prasad, A K et al. 2008. Novel nanotechnology platform: Design and synthesis. Polymer Preprints. 49: 1066-1067.
Prasad, A K et al. 2007. Selective biocatalytic deacylation studies on furanose triesters: a novel and efficient approach towards bicyclonucleosides. Organic Biomolecular Chemistry. 5: 3524-3530.
Kumar, V et al. 2007. Deacylation studies on furanose triesters using an Immobilized lipase: Synthesis of a key precursor for bicyclonucleosides. Chemical Communications.  : 2616-2617.
Kumar, A et al. 2007. Biocatalytic acylation studies on novel 3-aryl-3-hydroxymethyl-2,3-dihydro-4H-1-benzopyran -4-ones. Indian Journal of Chemistry. 46B: 1501-1510.
Kumar, S et al. 2007. Specificities of acetoxy derivatives of coumarins, biscoumarins, flavones, isoflavones and xanthones for acetoxy drug: protein transacetylase. European Journal of Medicinal Chemistry. 42: 447-455 .
Slambrouck, SV et al. 2007. A chromone analog inhibits TNF- induced expression of cell adhesion molecules on human endothelial cells via blocking TNF- activation. Bioorganic and Medicinal Chemistry 15, 2952-2962. 15: 2952-2962.
Sharma, S K et al. 2005. Tangeretin inhibits extracellular-signal-regulated kinase (ERK) phosphorylation. FEBS Letters. 579: 1665-1669.
Foti, MC et al. 2005. Biocatalytic routes towards pharmaceutically important precursors and novel polymeric systems. Pure and Applied Chemistry. 77: 209–226 .
Kumar, V et al. 2005. Biopolyphenolics as antioxidants: Studies under an Indo-Italian CSIR-CNR project.. J. Macromol. Sci., Pure and Applied Chemistry. 77: 91-101.
Watterson, A C et al. 2005. Mechanism of biochemical action of substituted 4-methylcoumarins. Part 11: Comparison of the specificities of acetoxy derivatives of 4-methylcoumarin and 4-phenylcoumarin to acetoxycoumarins: protein transacetylase. Bioorganic and Medicinal Chemistry. 13: 4300-4305.
Vanhoecke, BW et al. 2005. Indo-U.S. collaborative studies on biocatalytic generation of novel molecular architectures. Pure and Applied Chemistry. 77: 201-208 .
Raunak et al. 2005. New anti-invasive compounds: Results from the Indo-Belgian screening program. Pure and Applied Chemistry. 77: 65–74.
Sharma, Sunil . 2005. Microwave Mediated Synthesis of Spiro-(indoline-isoxazolidines): Mechanistic Study and Biological Activity Evaluation. Tetrahedron. 61: 5687-5697.

CONFERENCE PARTICIPATION/PRESENTATIONS

Organization of Conferences

Organizing Secretary: International Symposium on trends in drug discovery and development (T3D – 2010). 5 – 8 January 2009, organized by Department of Chemistry, University of Delhi.

Organizing Secretary: 6th Indo – Italian workshop on “Chemistry and Biology of Antioxidants”. 10 - 11 December 2009 – organized by Department of Chemistry, University of Delhi and Embassy of Italy.

Organizing Secretary: 3rd Indo – Italian Seminar on Green Chemistry. 9 December 2009 – organized by Department of Chemistry, University of Delhi and Embassy of Italy.

Conference  Presentations

Topics in Supramolecular Chemistry

Invited Lecture: Design and development of novel biocatalytic method for the synthesis of polymeric/ dendrimeric architectures. 23-27 June 2010, organized by Katholieke Universiteit Leuven, Belgium.

UGC-SAP sponsored ‘National Conference on Nanomaterials & Coordination Chemistry.

Invited Lecture: Biocatalytic synthesis of polymeric materials for drug delivery applications. 26 & 27 March 2010, organized by Department of Chemistry, Manipur University, Canchipur, Imphal. 

International Seminar on current trends in pharmaceutical research: focus on orphan diseases.

Invited Lecture: Design and synthesis of polymeric materials for drug delivery applications.10 January 2010, organized by NIPER, Hajipur C/o Rmrim. 

Research Projects (Major Grants/Research Collaboration)

DU-DST Purse Grant: Studies on the synthesis of acyloxy polyphenols, the substrates for calreticulin transacylase: Molecular mechanisms of acylation of functional proteins by acyloxy polyphenols utilizing recombinant clones of C, P and N domains of Calreticulin

Awards and distinctions

2007: Overseas Associateship award by Department of Biotechnology, Government of India; 1999: International Authors Award from the Royal Society of Chemistry (UK); 1999: Travel grant award by the Organizing Committee, Amsterdam Center for Drug Research; 1999: Travel grant award by International Union of Pure and Applied Chemistry and Biology held at University of Delhi, Delhi.